Showing posts with label medication. Show all posts
Showing posts with label medication. Show all posts

Friday, August 22, 2008

Girls, Women, People...Interrupted.

After watching the movie Girl, Interrupted for the Nth time, a few questions came to mind. Well, the first is more of a statement, which is how much I miss Angelina Jolie before she had 17 babies and stopped being a badass, i.e. became a blonde news reporter in Life or Something Like It. I think I actually cried tears, real tears, after watching that senseless, cliche, and awfully scripted waste of talent. She had so many breakthrough roles, took chances on being an outsider, and being different. The passion she put into those roles really showed on screen, managing to take even mediocre movies and make them compelling.




That being said, I truly love Girl, Interrupted; especially the way in which it tests boundaries, allows for characters to broken and unapologetic. But these people are incredibly likeable, seductive despite their demons, and similar to the novel (a true story) that it was based on, there aren't happy endings; and everyone's loose ends weren't always tied. It leaves you questioning humanity and its intricacies, its eccentricities; the way it lives, breathes, lashes out like a wild animal struggling to survive.

So many doctors still disagree and argue about the concept of mental illness. They found the movie controversial, stereotypical. But you can't take everything at face value, I took this movie for all of its themes, bare portrayals and ideas.

Not to mention Angelina Jolie acted her ass off!


I guess maybe the reason that I enjoyed this movie so intensely is because I've had personal experiences with many people with mental disorders, addictions, and social problems. Sometimes you struggle with the notions of responsibility, blame, misunderstanding, and that's what makes us human. It makes all of the other problems in the world seem so black and white, seem too immense or too small. It is tragic, but it is also reality. People can be so intriguing and yet so damaging.




Due to my melancholy mood, I decided to revisit the movie, fall in love with Angelina all over again, and pay homage to her fantastic performance with a few of my favorite lines:


Susanna: [narrating] Have you ever confused a dream with life? Or stolen something when you had the cash? Have you ever been blue? Or thought your train moving while sitting still? Maybe I was just crazy. Maybe it was the 60's. Or maybe I was just a girl... interrupted.

Lisa: You think your free? I'm free! You don't know what freedom is! I'm free. I can breathe. And you... will choke on your average fuckin' mediocre life!


Susanna: What the fuck are you doing Lisa?
Lisa: Playing the villain, baby, just like you want. I try to give you everything you want.
Susanna: No you don't.
Lisa: You wanted your file, I found you your file. You wanted out, I got you out. You needed money, I found you some. I'm fucking consistent! I told you the truth! I didn't write it down in a fucking book! I told you to your face. And I told Daisy to her face - what everybody knew and wouldn't say, and she killed herself. And I played the fucking villain, just like you wanted.
Susanna: Why would I want that?
Lisa: Because it makes you the good guy, sweet pea.



Georgina: Lisa? Is Daisy really getting out? Lisa: Yeah, she coughed up a big one.
Susanna: But how could - I mean she's... insane.
Lisa: Yeah, well that's what ther-rape-me's all about. That's why fuckin' Freud's picture's on every shrink's wall. He created a fuckin' industry. You lie down, you confess your secrets and you're saved. Ka-ching! The more you confess, the more they think about settin' you free. Susanna: But what if you don't have a secret?
Lisa: Then you're a lifer, like me.


Lisa: You know, there's too many buttons in the world. There's too many buttons and they're just- there's way too many just begging to be pressed. They're just begging to be pressed, you know? They're just - they're just begging to be pressed. And it makes me wonder, it really makes me fucking wonder, why doesn't anyone ever press mine? Why am I so neglected? Why doesn't anyone reach in and rip out the truth and tell me that I'm a fucking whore, or that my parents wish I were dead!
Susanna: Because you're dead already, Lisa!





Valerie: Did you enjoy the fresh air Lisa?
Lisa: Yeah I did Val. Thanks.
Valerie: Good, 'cause it's the last time you're leaving the ward.
Lisa: Is that a dare or a double dare?


Susanna: [reading from a book] "Borderline Personality Disorder. An instability of self-image, relationships and mood... uncertain about goals, impulsive in activities that are self-damaging, such as casual sex."
Lisa: I like that.
Susanna: "Social contrariness and a generally pessimistic attitude are often observed." [pauses] Susanna: Well that's me.
Lisa: That's everybody.


Lisa: We are very rare and we are mostly men.
Janet: Lisa thinks she's hot shit cause she's a sociopath.
Cynthia: I'm a sociopath.
Lisa: No, you're a dyke.


Lisa: Take one fuckin' step and I'll jam this in my aorta. [aiming a pen at her neck]
Valerie: Lisa, your aorta is in your chest.
Lisa: Good to know.


Ah, the simple beauty of it all. Well, on a side note I looked up a 'diag-nonsense' of Borderline Personality Disorder. According to the National Institute of Mental Health (NIMH), it is this:

"Borderline personality disorder (BPD) is a serious mental illness characterized by pervasive instability in moods, interpersonal relationships, self-image, and behavior. This instability often disrupts family and work life, long-term planning, and the individual's sense of self-identity. Originally thought to be at the "borderline" of psychosis, people with BPD suffer from a disorder of emotion regulation. While a person with depression or bipolar disorder typically endures the same mood for weeks, a person with BPD may experience intense bouts of anger, depression, and anxiety that may last only hours, or at most a day. These may be associated with episodes of impulsive aggression, self-injury, and drug or alcohol abuse. Distortions in cognition and sense of self can lead to frequent changes in long-term goals, career plans, jobs, friendships, gender identity, and values. Sometimes people with BPD view themselves as fundamentally bad, or unworthy. They may feel unfairly misunderstood or mistreated, bored, empty, and have little idea who they are. Such symptoms are most acute when people with BPD feel isolated and lacking in social support, and may result in frantic efforts to avoid being alone."

I don't know about you, but this sounds just like me on my period!


I just think all of these doctors need to stop medicating people and start listening. A good dose of Klonopin will put you to sleep, but when you wake up, things are exactly the same. Being bored, empty, or unsure is not an appropriate reason to pull out a prescription pad. Sometimes we all go a little crazy.








End rant, remove soapbox.




(Angelina, I heart you.)

Wednesday, August 13, 2008

Great News!

Even I can't find any sarcastic or cynical way to comment on this story. Besides the fact that I had to read the article 3 times to completely understand it, this is just awesome news in AIDS research:




"Woman May Hold Secret to AIDS Vaccine By Maggie Fox, Reuters

A woman who has never shown symptoms of infection with the AIDS virus may hold the secret to defeating the virus, U.S. researchers said on Tuesday.

Infected at least 10 years ago by her husband, the woman is able somehow to naturally control the deadly and incurable virus -- even though her husband must take cocktails of strong HIV drugs to control his.

She is a so-called "elite suppressor," and studies of her immune cells have begun to offer clues to how her body does it, the team at Johns Hopkins University in Baltimore said.

"This is the best evidence to date that elite suppressors can have fully pathogenic virus," said Dr. Joel Blankson, who led the study.
"The feeling was initially that they had defective virus," Blankson added in a telephone interview.

But the couple has been monogamous for at least 17 years, Blankson said, and tests show they are infected with the same strain of virus. What is different is the immune system of the wife, who cannot be named for privacy reasons.
"That's a good sign in terms of developing a therapeutic vaccine," Blankson said. Such a vaccine would not prevent infection but might be used to treat patients.

The AIDS virus infects at least 33 million people globally and more than a million in the United States. It has killed 25 million people since it was identified in the early 1980s.

New figures show 56,000 people are infected every year in the United states, mostly gay and bisexual men but also injecting drug users and their sexual partners, both male and female, as well as newborns and recipients of contaminated blood transfusions.

Both the man and the woman, who are from Baltimore, were diagnosed 10 years ago, Blankson said. The husband is a former injecting drug user.
Tests showed that immune cells known as CD8 T-cells from the wife stalled HIV replication by as much as 90 percent, while the husband's T-cells stopped it by only 30 percent, Blankson's team reported in the Journal of Virology.

Her virus has also mutated in apparent response to this immune attack, becoming weaker, while her husband's virus has remained strong.
"Elite suppression offers clues to vaccine researchers on many fronts: how CD8 killer T-cells can attack HIV and how a stronger immune response can force HIV into a permanent defensive state," Blankson said.

"We are trying to figure out exactly how the T-cells work in her to inhibit viral replication," he added. "We are just trying to see what kind of cytokines they make."

Cytokines are immune system signaling proteins. One thing the researchers have noticed is that while the husband's T-cells make just one, called gamma interferon, hers made both that one and another called TNF, or tumor necrosis factor.
That cannot be the whole story, though, because AIDS researchers have tried using such immune system proteins in patients and they did not work well.

And her immune cells seem to make the response only when they encounter the virus.
Another clue: the woman may have unusual activity in her human leukocyte antigen system, or HLA, Blankson said. This important component of the immune system helps recognize antigens -- protein identifiers -- of enemies such as bacteria and viruses.

Copyright 2008, Reuters"



The human body is freaking AMAZING. For the full article go here:


http://news.aol.com/health/article/woman-may-hold-secret-to-aids-vaccine/130997?icid=200100397x1207710705x1200404350